Accumulation of this molecule in aged individuals promotes tumour aggressioness, progression and metastasis

Gomes et al. report that MMA levels are significantly higher in the blood of healthy people over the age of 60 than in those under 30. The elevated level of MMA had not caused ill health in the individuals studied. However, the authors found that treating human cancer cells with serum from the blood of the older group, or with high concentrations of MMA, led them to adopt characteristics of metastatic cancer cells — those that can spread from a primary tumour to seed cancers elsewhere in the body. These characteristics include a loss of cell–cell attachment and an increase in mobility. When injected into mice, the cells formed metastatic tumours in the lungs.

The COVAXIN Efficacy story

In this #TWiS post, I describe in details the recent efficacy story of the Bharat Biotech and Indian Council of Medical Research – National Institute of Virology COVAXIN based on their recent The Lancet Infectious Diseases paper. This blog summarises the findings of phase 1, 2 trials and the interim analysis of phase 3 trial. Proud to have received the two doses of CAVIXN at AIIMS, New Delhi.
More power to indigenous vaccines working towards Atmanirbhar Bharat.

स्तन कैंसर: भारतीय परिपेक्ष्य में प्रबंधन एवं निदान

क्या आपने कभी कैंसर ट्रेन का नाम सुना है? अजीब है ना? भटिंडा, पंजाब से राजस्थान के बीकानेर शहर के बीच चलने वाली एक दैनिक रेलगाड़ी अपने 12 डिब्बों में 60 प्रतिशत से ज्यादा कैंसर पीड़ितों और उनके तीमारदारों को लेकर चलती है। मोहिंदर सिंह भी अपनी धर्मपत्नी बलबीर कौर के साथ इसमें यात्रा कर रहे हैं। शुरुआती जाँच में […]

A Big salute to COVID Warriors

Novel SARS-CoV-2 has slapped the world with a pandemic of a magnitude never witnessed in a century [1]. The whole world is under a complete lockdown. There is a prevalent sense of fear and insecurity. The global economy collapses [2], international travel ceases, streets deserted, and people locked into their homes. Under such tragic times, a set of people, termed […]

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